Background: The Cochrane Central Register of Controlled Trials (CENTRAL) is compiled from a number of sources, including PubMed and Embase. When you search in the search box on the top right of the site or on the Cochrane Evidence page, you can use Boolean operators and filters to refine your search.. Boolean operators. The Cochrane Library is a collection of databases in medicine and other healthcare specialties provided by the Cochrane Collaboration.At its core is a database of systematic reviews and meta-analyses which summarise and interpret the results of high-quality medical research. It includes 53 review groups that are based at research institutions worldwide. Example: Cochrane Wounds Specialized Register (searched 10 February 2015) The Cochrane Highly Sensitive Search Strategy (HSSS) for identifying randomized trials in MEDLINE has been developed and tested and can be added to your search strategy to retrieve RCTs & quasi RCTS. For example, if you search for paracetamol fever you will find results with either paracetamol or fever in the text. Appendix 4. Search strategy for identification of registration records. Ensure that CENTRAL, MEDLINE and Embase (if Embase is available to either the CRG or the review author), have been searched (either for the review or for the Review Group’s Specialized Register). OR searches - If you search for two or more words, you use an OR search by default. Template for a Search Report Form The following Cochrane Library via Wiley translation of the CAM on PubMed search strategy was developed in 2015 by Tamara Rader and updated in 2017 by Becky Skidmore. The Cochrane Library (named after Archie Cochrane) is a collection of databases in medicine and other healthcare specialties provided by Cochrane and other organizations. 6.3.3.2 Searching MEDLINE and EMBASE: specific issues via the Cochrane Register of Studies, or externally via CENTRAL). 6.3.3.1 Searching The Cochrane Central Register of Controlled Trials (CENTRAL): specific issues. Example of a scope/topic search for CENTRAL; Appendix 6. Cochrane (previously known as the Cochrane Collaboration) is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. Example of a scope/topic search (MEDLINE) Appendix 5. The Cochrane Central Register of Controlled Trials (CENTRAL) and MEDLINE, together with Embase (if access to Embase is available to the review team) should be searched for all Cochrane Reviews. Box 6.3.c: Example of exclusion of MEDLINE and EMBASE records when searching CENTRAL. Example of the structure of a search strategy for a Cochrane review (CENTRAL) Appendix 8. Introductory text. a The number of ICTRP or ClinicalTrials.gov records in CENTRAL was estimated by limiting the publication year up to and including 2019 The date range (for databases) or search date (for study registers) of each search must be listed with each database; for example, CENTRAL (year, issue number), and for most other databases, such as MEDLINE, it should be in the form 'MEDLINE (year to day month year)'. Abbreviations: CENTRAL, Cochrane Central Register of Controlled Trials; ICTRP, International Clinical Trials Registry Platform; ID, Identifier. At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses which summarize and interpret the results of medical research. 6.3.3 Searching CENTRAL, MEDLINE and EMBASE: specific issues. Search the Cochrane Review Group’s (CRG’s) Specialized Register (internally, e.g. Example of the structure of a search strategy for a Cochrane review (MEDLINE) Appendix 7. Since 2017, we have increased the number of sources feeding into CENTRAL and improved the efficiency of our processes through the use of APIs, machine learning and crowdsourcing.

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